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Pre-treatment of the PBMCs with antioxidants, tiron, L -histidine, and D -mannitol, reduced the observed number of lesions to the same level as the untreated sample, implicating superoxide, singlet oxygen, and hydroxyl radicals, respectively, in lesion formation

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Seventy-five women were assessed, and a subgroup with reduced urinary excretion of the melatonin metabolite 6-sulfatoxymelatonin was divided between AEDG and placebo exposure for 20 days

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